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Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues (英語) ハードカバー – 2014/4/8

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A critically important and startling look at the harmful effects of overusing antibiotics, from the field's leading expert
Tracing one scientist's journey toward understanding the crucial importance of the microbiome, this revolutionary book will take readers to the forefront of trail-blazing research while revealing the damage that overuse of antibiotics is doing to our health: contributing to the rise of obesity, asthma, diabetes, and certain forms of cancer. In "Missing Microbes," Dr. Martin Blaser invites us into the wilds of the human microbiome where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now, this invisible eden is being irrevocably damaged by some of our most revered medical advances antibiotics threatening the extinction of our irreplaceable microbes with terrible health consequences. Taking us into both the lab and deep into the fields where these troubling effects can be witnessed firsthand, Blaser not only provides cutting edge evidence for the adverse effects of antibiotics, he tells us what we can do to avoid even more catastrophic health problems in the future."

レビュー

"Missing Microbes adds a new frontier towards understanding vastly underappreciated key contributions of the human microbiome to health and human disease. As a world leader in defining the microbiome, Dr. Blaser explains how disturbing its natural balance is affecting common conditions such as obesity and diabetes, long thought of as primarily nutrition and lifestyle related problems. Blaser's carefully and convincingly written book outlines new dimensions that need to be considered in fighting a number of common diseases and in promoting health and well-being." --Richard Deckelbaum, Director, Institute of Human Nutrition, Columbia University "In a world that turns to antibiotics for every infection of the ear, sinuses, or skin, Dr. Blaser makes even the most nervous parent think twice about giving her child these ubiquitous drugs. Dr. Blaser contends that the excessive use of antibiotics--especially in children--is at the root of our most serious emerging modern maladies, from asthma and food allergies to obesity and certain cancers. He walks us through the science behind his theories and examines the duality of microbes, both as essential agents of good health and perpetrators of sickness. At a time when the Centers for Disease Control and Prevention is campaigning for more judicious use of antibiotics, Dr. Blaser delivers a thoughtful, well-written and compelling case for why doctors need to be more cautious about prescribing these medications and why consumers should consider alternatives before taking them." --Nirav R. Shah, MD, MPH, Commissioner of Health, New York"Dr. Blaser's credibility as a world class scientist and physician makes this exploration of our body's microbial world particularly provocative. "Missing Microbes" will make you rethink some fundamental ideas about infection. Blaser's gift is to write clearly and to take the reader on a fascinating journey through the paradoxes and insights about the teeming world within us."--Abraham Verghes

"Credit Blaser for displaying the wonders and importance of a vast underworld we are jeopardizing but cannot live without."--"Kirkus""Missing Microbes adds a new frontier towards understanding vastly underappreciated key contributions of the human microbiome to health and human disease. As a world leader in defining the microbiome, Dr. Blaser explains how disturbing its natural balance is affecting common conditions such as obesity and diabetes, long thought of as primarily nutrition and lifestyle related problems. Blaser's carefully and convincingly written book outlines new dimensions that need to be considered in fighting a number of common diseases and in promoting health and well-being." --Richard Deckelbaum, Director, Institute of Human Nutrition, Columbia University "In a world that turns to antibiotics for every infection of the ear, sinuses, or skin, Dr. Blaser makes even the most nervous parent think twice about giving her child these ubiquitous drugs. Dr. Blaser contends that the excessive use of antibiotics--especially in children--is at the root of our most serious emerging modern maladies, from asthma and food allergies to obesity and certain cancers. He walks us through the science behind his theories and examines the duality of microbes, both as essential agents of good health and perpetrators of sickness. At a time when the Centers for Disease Control and Prevention is campaigning for more judicious use of antibiotics, Dr. Blaser delivers a thoughtful, well-written and compelling case for why doctors need to be more cautious about prescribing these medications and why consumers should consider alternatives before taking them." --Nirav R. Shah, MD, MPH, Commissioner of Health, New York"Dr. Blaser's credibility as a world class scientist and physician makes this exploration of our body's microbial world particularly provocative. "Missing Microbes" will make you rethink some fundamental ideas about infection. Blaser's gift is to write clearly an

"An engrossing examination of the relatively unheralded yet dominant form of life on Earth." --"Publishers Weekly "(starred review)"Blaser's "Missing Microbes "is a masterful work of preventative health and superb science writing." --"Booklist "(starred review)"Credit Blaser for displaying the wonders and importance of a vast underworld we are jeopardizing but cannot live without."--"Kirkus""Missing Microbes adds a new frontier towards understanding vastly underappreciated key contributions of the human microbiome to health and human disease. As a world leader in defining the microbiome, Dr. Blaser explains how disturbing its natural balance is affecting common conditions such as obesity and diabetes, long thought of as primarily nutrition and lifestyle related problems. Blaser's carefully and convincingly written book outlines new dimensions that need to be considered in fighting a number of common diseases and in promoting health and well-being." --Richard Deckelbaum, Director, Institute of Human Nutrition, Columbia University "In a world that turns to antibiotics for every infection of the ear, sinuses, or skin, Dr. Blaser makes even the most nervous parent think twice about giving her child these ubiquitous drugs. Dr. Blaser contends that the excessive use of antibiotics--especially in children--is at the root of our most serious emerging modern maladies, from asthma and food allergies to obesity and certain cancers. He walks us through the science behind his theories and examines the duality of microbes, both as essential agents of good health and perpetrators of sickness. At a time when the Centers for Disease Control and Prevention is campaigning for more judicious use of antibiotics, Dr. Blaser delivers a thoughtful, well-written and compelling case for why doctors need to be more cautious about prescribing these medications and why consumers should consider alternatives before taking them." --Nirav R. Shah, MD, MPH, Commissioner of Health, New York"D

"Unlike some books on medicine and microbes, Dr. Blaser's doesn't stir up fears of exotic diseases or pandemic 'superbugs' resistant to all known drugs. He focuses on a simpler but more profound concern: the damage that modern life inflicts on the vast number of microbes that all of us, even healthy people, carry inside us at all times."--"The Wall Street Journal "

""Missing Microbes" presents a surprisingly clear perspective on a complex problem."--"Philadelphia Inquirer ""In "Missing Microbes, " Martin Blaser sounds [an] alarm. He patiently and thoroughly builds a compelling case that the threat of antibiotic overuse goes far beyond resistant infections."--"Nature""Blaser presents a sensible plan for reclaiming our microbial balance and avoiding calamity both as a society...and on an individual level." --"Discover ""An engrossing examination of the relatively unheralded yet dominant form of life on Earth." --"Publishers Weekly "(starred review)"Blaser's "Missing Microbes "is a masterful work of preventative health and superb science writing." --"Booklist "(starred review)"Credit Blaser for displaying the wonders and importance of a vast underworld we are jeopardizing but cannot live without."--"Kirkus""Missing Microbes adds a new frontier towards understanding vastly underappreciated key contributions of the human microbiome to health and human disease. As a world leader in defining the microbiome, Dr. Blaser explains how disturbing its natural balance is affecting common conditions such as obesity and diabetes, long thought of as primarily nutrition and lifestyle related problems. Blaser's carefully and convincingly written book outlines new dimensions that need to be considered in fighting a number of common diseases and in promoting health and well-being." --Richard Deckelbaum, Director, Institute of Human Nutrition, Columbia University "In a world that turns to antibiotics for every infection of the ear, sinuses, or skin, Dr. Blaser makes even the most nervo

"The weight of evidence behind Dr. Blaser's cautions about antibiotics is overwhelming."--"The New York Times ""Unlike some books on medicine and microbes, Dr. Blaser's doesn't stir up fears of exotic diseases or pandemic 'superbugs' resistant to all known drugs. He focuses on a simpler but more profound concern: the damage that modern life inflicts on the vast number of microbes that all of us, even healthy people, carry inside us at all times."--"The Wall Street Journal "

""Missing Microbes" presents a surprisingly clear perspective on a complex problem."--"Philadelphia Inquirer ""In "Missing Microbes, " Martin Blaser sounds [an] alarm. He patiently and thoroughly builds a compelling case that the threat of antibiotic overuse goes far beyond resistant infections."--"Nature""Readable and challenging, "Missing Microbes" provides a stimulus with which to probe existing dogma." --"Science ""Blaser presents a sensible plan for reclaiming our microbial balance and avoiding calamity both as a society...and on an individual level." --"Discover """Missing Microbes" blazes a new trail."--"The Huffington Post""An engrossing examination of the relatively unheralded yet dominant form of life on Earth." --"Publishers Weekly "(starred review)"Blaser's "Missing Microbes "is a masterful work of preventative health and superb science writing." --"Booklist "(starred review)"Credit Blaser for displaying the wonders and importance of a vast underworld we are jeopardizing but cannot live without."--"Kirkus""Missing Microbes adds a new frontier towards understanding vastly underappreciated key contributions of the human microbiome to health and human disease. As a world leader in defining the microbiome, Dr. Blaser explains how disturbing its natural balance is affecting common conditions such as obesity and diabetes, long thought of as primarily nutrition and lifestyle related problems. Blaser's carefully and convincingly written book outlines new dimensions that need to be considered in fighting a number of common diseases and in promoting health and well-being." --Richard Deckelbaum, Director, Institute of Human Nutrition, Columbia University "In a world that turns to antibiotics for every infection of the ear, sinuses, or skin, Dr. Blaser makes even the most nervous parent think twice about giving her child these ubiquitous drugs. Dr. Blaser contends that the excessive use of antibiotics--especially in children--is at the root of our most serious emerging modern maladies, from asthma and food allergies to obesity and certain cancers. He walks us through the science behind his theories and examines the duality of microbes, both as essential agents of good health and perpetrators of sickness. At a time when the Centers for Disease Control and Prevention is campaigning for more judicious use of antibiotics, Dr. Blaser delivers a thoughtful, well-written and compelling case for why doctors need to be more cautious about prescribing these medications and why consumers should consider alternatives before taking them." --Nirav R. Shah, MD, MPH, Commissioner of Health, New York"Dr. Blaser's credibility as a world class scientist and physician makes this exploration of our body's microbial world particularly provocative. "Missing Microbes" will make you rethink some fundamental ideas about infection. Blaser's gift is to write clearly and to take the reader on a fascinating journey through the paradoxes and insights about the teeming world within us."--Abraham Verghese MD, author of "Cutting for Stone""I have often wondered why kids today seem to have such a high incidence of asthma, ear infections, allergies, reflux esophagitis and so many other conditions that I rarely saw growing up. This mystery has been solved by the pioneering work of Dr. Marty Blaser and is communicated brilliantly in "Missing Microbes." I cannot emphasize enough the importance of this book to your own health, the health of your children and grandchildren and to the health of our country. "Missing Microbes "is truly a must read." --Arthur Agatston, author of "The South Beach Diet""We live today in a world of modern plagues, defined by the alarming rise of asthma, diabetes, obesity, food allergies, and metabolic disorders. This is no accident, argues Dr. Blaser, the renowned medical researcher: the common link being the destruction of vital bacteria through the overuse of broad-spectrum antibiotics. "Missing Microbes" is science writing at its very best--crisply argued and beautifully written, with stunning insights about the human microbiome and workable solutions to an urgent global crisis." --David M. Oshinsky, author of the Pulitzer Prize-winning "Polio: An American Story""Why is it that you are fat, your son has asthma, and your 13-year-old daughter is six feet tall? Dr. Blaser says your bodies are missing vital, beneficial bacteria and I guarantee that after reading this book you will agree. Take a pass on the antibiotics and read "Missing Microbes.""--Laurie Garrett, Pulitzer Prize winning writer and Senior Fellow for Global Health at the Council on Foreign Relations

The weight of evidence behind Dr. Blaser's cautions about antibiotics is overwhelming. "The New York Times"

Unlike some books on medicine and microbes, Dr. Blaser's doesn't stir up fears of exotic diseases or pandemic 'superbugs' resistant to all known drugs. He focuses on a simpler but more profound concern: the damage that modern life inflicts on the vast number of microbes that all of us, even healthy people, carry inside us at all times. "The Wall Street Journal"

"Missing Microbes" presents a surprisingly clear perspective on a complex problem. "Philadelphia Inquirer"

In "Missing Microbes, " Martin Blaser sounds [an] alarm. He patiently and thoroughly builds a compelling case that the threat of antibiotic overuse goes far beyond resistant infections. "Nature"

Readable and challenging, "Missing Microbes" provides a stimulus with which to probe existing dogma. "Science"

Blaser presents a sensible plan for reclaiming our microbial balance and avoiding calamity both as a society...and on an individual level. "Discover"

"Missing Microbes" blazes a new trail. "The Huffington Post"

An engrossing examination of the relatively unheralded yet dominant form of life on Earth. "Publishers Weekly (starred review)"

Blaser's "Missing Microbes "is a masterful work of preventative health and superb science writing. "Booklist (starred review)"

Credit Blaser for displaying the wonders and importance of a vast underworld we are jeopardizing but cannot live without. "Kirkus"

Missing Microbes adds a new frontier towards understanding vastly underappreciated key contributions of the human microbiome to health and human disease. As a world leader in defining the microbiome, Dr. Blaser explains how disturbing its natural balance is affecting common conditions such as obesity and diabetes, long thought of as primarily nutrition and lifestyle related problems. Blaser's carefully and convincingly written book outlines new dimensions that need to be considered in fighting a number of common diseases and in promoting health and well-being. "Richard Deckelbaum, Director, Institute of Human Nutrition, Columbia University"

In a world that turns to antibiotics for every infection of the ear, sinuses, or skin, Dr. Blaser makes even the most nervous parent think twice about giving her child these ubiquitous drugs. Dr. Blaser contends that the excessive use of antibiotics--especially in children--is at the root of our most serious emerging modern maladies, from asthma and food allergies to obesity and certain cancers. He walks us through the science behind his theories and examines the duality of microbes, both as essential agents of good health and perpetrators of sickness. At a time when the Centers for Disease Control and Prevention is campaigning for more judicious use of antibiotics, Dr. Blaser delivers a thoughtful, well-written and compelling case for why doctors need to be more cautious about prescribing these medications and why consumers should consider alternatives before taking them. "Nirav R. Shah, MD, MPH, Commissioner of Health, New York"

Dr. Blaser's credibility as a world class scientist and physician makes this exploration of our body's microbial world particularly provocative. "Missing Microbes" will make you rethink some fundamental ideas about infection. Blaser's gift is to write clearly and to take the reader on a fascinating journey through the paradoxes and insights about the teeming world within us. "Abraham Verghese MD, author of Cutting for Stone"

I have often wondered why kids today seem to have such a high incidence of asthma, ear infections, allergies, reflux esophagitis and so many other conditions that I rarely saw growing up. This mystery has been solved by the pioneering work of Dr. Marty Blaser and is communicated brilliantly in "Missing Microbes." I cannot emphasize enough the importance of this book to your own health, the health of your children and grandchildren and to the health of our country. "Missing Microbes "is truly a must read. "Arthur Agatston, author of The South Beach Diet"

We live today in a world of modern plagues, defined by the alarming rise of asthma, diabetes, obesity, food allergies, and metabolic disorders. This is no accident, argues Dr. Blaser, the renowned medical researcher: the common link being the destruction of vital bacteria through the overuse of broad-spectrum antibiotics. "Missing Microbes" is science writing at its very best--crisply argued and beautifully written, with stunning insights about the human microbiome and workable solutions to an urgent global crisis. "David M. Oshinsky, author of the Pulitzer Prize-winning Polio: An American Story"

Why is it that you are fat, your son has asthma, and your 13-year-old daughter is six feet tall? Dr. Blaser says your bodies are missing vital, beneficial bacteria and I guarantee that after reading this book you will agree. Take a pass on the antibiotics and read "Missing Microbes." "Laurie Garrett, Pulitzer Prize winning writer and Senior Fellow for Global Health at the Council on Foreign Relations""

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  • ハードカバー: 273ページ
  • 出版社: Henry Holt & Co (2014/4/8)
  • 言語: 英語
  • ISBN-10: 0805098100
  • ISBN-13: 978-0805098105
  • 発売日: 2014/4/8
  • 商品パッケージの寸法: 16 x 2.7 x 23.9 cm
  • おすすめ度: 5つ星のうち 5.0 2件のカスタマーレビュー
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1型糖尿病、肥満、逆流性食道炎、アレルギー、炎症性腸疾患と抗生物質の乱用(人間だけでなく家畜用も)、自閉症と帝王切開の関連性について詳しく述べられていて、英文も難しくないので、読みやすくためになった。おそらく日本はアメリカ以上に抗生物質が処方されている?身につまされた。
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Amazon.com: 5つ星のうち 4.7 240 件のカスタマーレビュー
1 人中、1人の方が、「このレビューが参考になった」と投票しています。
5つ星のうち 5.0 A laid back, informative MUST READ for everybody!! 2016/6/7
投稿者 Sara - (Amazon.com)
形式: ペーパーバック Amazonで購入
I just closed this book and I felt the need to immediately review it. As a student microbiologist, chemist, and current medical worker, I cannot recommend this book highly enough. Dr. Blaser lays out the complexity and wonder of the microscopic world in a way that's fathomable to a general audience. He approaches the dense subject matter of the (human) microbiome in a gentle, laid back yet informative manner, making this book a relatively simple read for even those with little to no scientific background. I will be recommending this book to everyone I know, especially those working in the medical, or any science driven, field (as well as any politician I may come across, ha!) Even if you know nothing about microbiology, and your last science class was in high school, I urge you to read this informative masterpiece. I cannot overstate the urgency of this topic, and I believe this book can provide anyone with a perfect segue into the crisis of the overuse of antibiotics (or the rise of "superbugs", if that catches your attention more.)

This is now one of my favorite books! Give it a try!
3 人中、3人の方が、「このレビューが参考になった」と投票しています。
5つ星のうち 5.0 Great book on general gut biome issues, more focussed on stomach than lower down. 2014/10/20
投稿者 swimdb - (Amazon.com)
形式: ハードカバー Amazonで購入
This book has good chapters on various aspects of gut biome issues and antibiotics. The author gives clear explanations and has extensive expertise in the field.

One thing that is slightly misleading, though the major issues are covered in a general manner a lot of the specifics are focussed on Helicobacter Pylori, which is a stomach centered bacteria rather than something from lower down. I was expecting more coverage of the range of bacteria in the intestinal biome. This in no way detracts from the quality of the book as a some of the issues with H. Pylori seems to be those of the general intestinal biome also.

Overall there is quite a wide and big picture view as well as the focus on H Pylori case studies. For example the author mentions work on Caesarian birth innoculation and other clean hypothesis issues. The case studies themselves are presented in a good scientific manner with descriptions of the protocols and evidence for the findings. Also this book made me want to go work with Dr. Blaser on studies like the one he described. Important work.
5 人中、5人の方が、「このレビューが参考になった」と投票しています。
5つ星のうち 4.0 Some Well Referenced, Other Avant-Garde Even Hypothetical 2014/5/29
投稿者 Lady LiberTEA - (Amazon.com)
形式: ハードカバー Amazonで購入
Microbiologist enviro-toxicologist PhD hubby enjoyed this book and says that it includes:

1) a well-referenced examination of antibiotic history, challenges, and cost/benefit;

2) a premise that C-section births miss the transfer of gut flora from propinquity to the anus; and

3) an avant-garde premise that the H.Pylori Bacteria, known for contributing to ulceration of an inflamed stomach, also can be beneficial, citing author's work with mice my husband believes too different from human for comparison.
5つ星のうち 5.0 An amazing adventure 2016/7/25
投稿者 KorinRex - (Amazon.com)
形式: ハードカバー Amazonで購入
Absolutely one of the most interesting books I have ever read. Would highly recommend to someone looking for a gift for a person with a budding interest in microbiology. Although the core concepts are about a technical subject, the book is written in a way that would be easy for most readers to process with little to no background knowledge of microbiology. Each bit of new information is preceded by, and then told in conjunction with, an anecdotal story by the author, which helps to give context to each new idea. I really enjoyed and admired how he was able to include scientific information with interesting storytelling in a very cohesive manner.
5つ星のうち 5.0 Mind blown at intricacies of the wee animalcules inside of us. 2016/6/3
投稿者 Harlan Kanoa Sheppard - (Amazon.com)
形式: Kindle版 Amazonで購入
Like most well-read denizens of the internet's scientific literature, I was aware that there was something going on with the microbes that live in our gut. I couldn't have fathomed the associations that actually exist, or the depth of them. To the credit of the author, Dr. Blaser doesn't make concrete claims in the absence of evidence, but doesn't mince words about links that warrant further investigation.

As a study of microbiology, I would suggest this book to any first or second year students going into medical laboratory science as inspiring and eye-opening toward the next decade in medicine.

This was an enlightening view
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