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商品の説明
内容説明
In RNA: Life's Indispensable Molecule, Jim Darnell provides a comprehensive and captivating account of RNA research, illuminated by his own life-long and celebrated engagement in the field. Darnell describes how scientists unraveled fundamental questions about the biochemical and genetic importance of RNA--how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, and how RNA molecules likely initiated life on Earth. With a scope extending from the early 20th century to the present day, and with the clarity expected from an accomplished textbook author, he conveys the intellectual context in which these questions first arose and explains how the key experiments were structured and answers obtained. The book is geared towards scientists from the graduate level on up, and will particularly appeal to active investigators in RNA biology, educators of molecular biology and biochemistry, and science historians.
著者について
James E. Darnell, Jr., M.D. has been Vincent Astor Professor at The Rockefeller University since 1974. His career has included poliovirus research with Harry Eagle at the National Institutes of Health, research with Franois Jacob at the Pasteur Institute in Paris, and academic appointments at the Massachusetts Institute of Technology, Albert Einstein College of Medicine, and Columbia University. He has mentored over 120 doctoral students and postdoctoral scientists. From the very beginning of his first lab at MIT, Darnell, his students and postdocs have studied RNA, its synthesis, processing, and transcriptional regulation.
Darnell is a member of the National Academy of Sciences and has received numerous awards, including the 2003 National Medal of Science and the 2002 Albert Lasker Award for Special Achievement in Medical Science. He is the coauthor, with S.E. Luria, of General Virology (Wiley) and the founding author with Harvey Lodish and David Baltimore of Molecular Cell Biology
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4 人中、3人の方が、｢このレビューが参考になった｣と投票しています。
It is mostly about reasearch milstones in the field of RNA research
2011/9/5
形式:ハードカバー|Amazonが確認した購入
As nowadays we are benefiting from the the many outcomes of high-throughput molecular biology, the articulate hypothesis-driven research is often being neglected. This book provides some interesting glimpse into those historical discoveries regarding the RNA world from an era which was poor in prior knowledge and had to heavily rely on hypothesis-driven research. If you are a student and you look for "fundamentals of the RNA world" of today- you may want to look for other books. Teachers and senior researches will find this book extremely interesting, if they have the time for it.
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