Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed, almost doubling the amount of chemical information with an additional volume.
As in the predecessor, a short introductory section covers the theoretical background and evaluates currently available instrumentation and equipment. The main part of the book then goes on to systematically survey the complete range of published microwave-assisted synthesis methods from their beginnings in the 1990s to mid-2011, drawing on data from more than 5,000 reports and publications. Throughout, the focus is on those reactions, reagents and reaction conditions that work, and that are the most relevant for medicinal and natural products chemistry. A much expanded section is devoted to combinatorial, high-throughput and flow chemistry methods.
C. Oliver Kappe is Professor of organic chemistry and Director of the Doppler Laboratory for Microwave Chemistry at the University
of Graz, Austria, where he also received his doctorate in 1992. After postdoctoral work with CurtWentrup at the University of Queensland, Australia, and with Albert Padwa at Emory University, Atlanta, USA, he returned to the University of Graz and became Associate Professor in 1999. He has been a visiting scientist at the Scripps Research Institute as well as the Tokyo Institute of Technology. Professor Kappe's current research focuses on microwave-assisted synthesis and continuous flow processing.
Alexander Stadler studied chemistry at the University of Graz, Austria, where he also obtained his doctoral degree for studies on microwave-accelerated reactions in solution and on solid phase in the group of C. Oliver Kappe. He conducted postdoctoral research work on microwave-assisted transition metal-catalyzed coupling reactions in the group of Mats Larhed at the University of Uppsala, Sweden. In 2004 he joined Anton Paar GmbH in Graz where he is currently working as product manager for microwave synthesis instruments.
Doris Dallinger obtained her PhD degree in the group of C. Oliver Kappe at the University of Graz, Austria, on projects related to microwave chemistry and high-throughput synthesis. After postdoctoral research work at the Christian Doppler Laboratory for Microwave Chemistry she joined the faculty of the University of Graz as staff scientist in 2011.