This book is the best and worst of the High Yield series.
What is does right: Allows a quick easy read, without too much detail to bog you down. Only real use I can see in preparing for USMLE is to read this book to gear you up for studying and to get some dormant material back into circulation.
What it does wrong: It does cover SOME high yield content, but it is greatly lacking in the details that allow you to differentiate the content (ex. It never mentions gene translocations associated with specific cancers/leukemia's/Lymphomas, poor description of age brackets for leukemia's). T8:14 WILL be on the USMLE. No two ways around it. As another random example, there is NO mention of many microorganisms/viral pathogens like Parvovirus. AFP? ACD? "chirp chirp" is what this book says all to often.
Conclusion: Do NOT think that this book is a "complete" review for USMLE. It is severely lacking in crucial details. It should only be used as a primer for hard core prep - if that. Time is of the essence, so why waste it on intro material. The core of your studying should be First Aid (with additional resource books in weak areas), Goljan Rapid Review Pathology (new ed out late 2006), Case reviews (I like First Aid Cases, and the Platinum Vignettes series), and last, some type of Qbank (I went with usmleRx/FA).