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Crystallography Made Crystal Clear, Third Edition: A Guide for Users of Macromolecular Models (Complementary Science) (英語) ペーパーバック – 2006/3/2
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Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs.
* Helps readers to understand where models come from, so they don't use them blindly and
* Provides many visual and geometric models for understanding a largely mathematical method
* Allows readers to judge whether recently published models are of sufficiently high quality and detail to be useful in their own work
* Allows readers to study macromolecular structure independently and in an open-ended fashion on their own computers, without being limited to textbook or journals illustrations
* Provides access to web tools in a format that will not go out of date. Links will be updated and added as existing resources change location or are added
Praise for the first edition
"Well-written...in my opinion is now the best reference for noncrystallographers who want to know more about X-ray diffraction and the data that result from it."
-AMERICAN JOURNAL OF PHYSIOLOGY
Amazon.com で最も参考になったカスタマーレビュー (beta)
It is important to note that the book is still far from "crystal clear"! The portion of the book dealing with the physics of x-ray diffraction is very mysterious--definately dig out the old college physics textbook and read about diffraction when you find yourself confused. Also, the mathematics presented in the middle chapters of the book are way beyond the level that biochemists must deal with on a regular basis. An understanding of multi-variable calculus is important for these chapters.
Overall, the book is a must-read for anyone interested in structural biology, with the exception of several chapters regarding the mathematics that can be skimmed over. And the webpage associated with the book is an excellent resource.
My advice: if you just want to pass the class and don't care about the subject, go with this book. If, however, you really want to understand what crystallography is about, you need to read either the great beginner's book by Werner Massa: Crystal Structure Determination or the more protein crystallography oriented but equally great beginners book by Jenny Glusker and Kenneth Trueblood: Crystal Structure Analysis -- A Primer. Once you have digested the Massa or the Glusker/Trueblood, you can work your way through the book edited by Carmelo Giacovazzo: Fundamentals of Crystallography.
After reading and understanding the Massa or Glusker/Trueblood and the Giacovazzo, you'll be ready to survive a discussion with any crystallographer any time. (What is more: you will enjoy the discussion!) The book by Gale Rhodes, however, will only get you over the exam and you'll miss out on the great fun crystallography can be.
EDIT on 12/12/2010:
A new edition of the Glusker Trueblood has come out: Crystal Structure Analysis: A Primer. The classic has been brought up-to-date and there really is no excuse any more for reading any other introductory textbook than the Glusker/Trueblood. Especially not the book by Gale Rhodes.
For non-crystallographers, this book will teach enough about crystallography to allow you to read crystal structure articles and understand what is meant by all of the used statistics and such.
For apprentice crystallographers, this is a wonderful intro into the field. Master the book, then move on to harder books to master it.
Highly recommended. I still go back to it, when I teach people, to help me explain in the way that Gale Rhodes does!